Take a look at this engine's power and torque curves, for example.
Despite it's torque peaking at 4500Rpm (screw ethanol), that obviously isn't the most fuel efficient RpM to reference against any cruise control target. Do note, however, the ever-so-slightly lesser peak, around 2500 RpM.
If I didn't know anything else, I'd strive to set the cruise control so that this particular engine stayed at or under 2500 RpM.
Since I'd prefer to know more, I'd ask a GM technician, or someone familiar with the stock PCM settings, "at what RpM does the EGR Valve stop working?"
Keep RpMs under the lesser of the two.
While I have the tech's ear, I'll also ask, when coasting down, "at what engine RpM does DFCO engage?", and "at what RpM does it disengage to try to keep the engine from stalling?
I'd try to keep the engine in that RpM window.
When a car is equipped with a lean burn catalyst, the PCM will permit Air:Fuel ratios approaching 30:1 from time to time, provided the throttle is managed deftly, and NO acceleration whatsoever is called for; ANY additional throttle opening resets the target A:F ratio @ 14.7:1.
Generally, the heavier the acceleration/load, and the higher the RpMs, the richer the A:F ratio needed. (My old Caprice will cruise at 16:1 under 60MpH in 4th Gear, but before I had it reprogrammed, Wide Open Throttle Power Enrichment would cause the A:F to approach 10:1. With the reprogramming. WOT PE sets a target A:F of about 12.6:1.)Also, in reality, the more fuel combusted, the more energy wasted as heat.
Finally, when accelerating, I'd use 1st gear to get out of the blocks, then use the highest gear reasonably possible to keep the engine RpMs within the above windows. This may involve skipping a gear or two [-or three, in the case of nearly any GM engine attached to a Getrag Six Speed Gearbox].
If I had to guess without any of the above info, assuming a four cylinder engine like the one above, I'd stay between 1000 & 2500 RpM, whether accelerating, cruising, or decelerating. (Hey, that was a decent guess, no?)
I'd wager that Wayne Gerdes, or other hypermilers, strive to stay under 2000 RpM whenever reasonably possible, but I simply don't have that kind of time.
(Note that if your engine is equipped with both a manual gearbox AND a wireless throttle, the accelerator pedal doesn't decide how far the throttle should open by itself; the PCM makes this decision against a matrix table referencing Throttle Position, selected gear, and present speed.
In other words, the PCM will not allow the throttle to open or close too quickly.
Then again, if your accelerator IS connected to the throttle, or the PCM doesn't mind a huge delta throttle angle, you can try the
Throttle Filter suggested in this article.)